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Profiles

Aeras Global TB Vaccine Foundation

The Aeras Global TB Vaccine Foundation was an American nonprofit product development organization based in Rockville, Maryland.

Aeras worked to develop vaccines against tuberculosis with a number of partners, including adenoviral vector vaccines with Crucell (now known as Janssen) and second-generation fusion-protein vaccines with Statens Serum Institut.

History

Aeras was founded in 1997 to “help develop new concepts and tools to control the global TB epidemic.”[1]

In February 2004, Aeras received a 5-year US$82.9 million grant from the Bill & Melinda Gates Foundation. Aeras and the Gates Foundation co-funded an “infant and adolescent TB Vaccine Site preparation study” alongside the European & Developing Countries Clinical Trials Partnership (EDCCTP) at the Infectious Diseases Institute in Uganda.[2]

Organization

Aeras was partnered with the Medicines for Malaria Venture to develop antimicrobial products.[3]

Funding

Aeras was funded by:[4][5]

  • Australian Aid
  • Bill & Melinda Gates Foundation
  • Centers for Disease Control and Prevention (CDC)
  • China National Biotec Group (CNBG)
  • Chinese Center for Disease Control and Prevention (CCDC)
  • Crucell
  • Danish International Development Agency (DANIDA)
  • Dutch Ministry of Foreign Affairs
  • Emergent BioSolutions
  • European & Developing Countries Clinical Trials Partnership (EDCCTP)
  • Food and Drug Administration (FDA)
  • Geisel School of Medicine at Dartmouth
  • GlaxoSmithKline
  • Global Health Innovative Technology Fund (GHITF)
  • Infectious Disease Research Institute (IDRI)
  • Okairos
  • Oregon Health & Science University (OHSU)
  • Pasteur Institute of Lille
  • Research Council of Norway
  • Sanofi Pasteur
  • Statens Serum Institut
  • Stop TB Partnership
  • TuBerculosis Vaccine Initiative (TBVI)
  • UK Aid
  • United States Department of Defense (DoD)
  • University of Oxford
  • Wellcome Trust

Network

Participants in Aeras' clinical trial network included:

  • Aurum Institute
  • Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Children’s Infectious Diseases Clinical Research Unit (KID-CRU)
  • Desmond Tutu HIV Center
  • HIV Vaccine Trials Network (HVTN)
  • International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT)
  • Kenya Medical Research Institute (KEMRI)
  • National Institute for Medical Research, Tanzania (NIMR)
  • Perinatal HIV Research Unit (PHRU)
  • Setshaba Research Centre
  • South African Tuberculosis Vaccine Initiative (SATVI)
  • TASK Applied Science
  • University of Cape Town Lung Institute (UCTLI)
  • Wellcome Centre for Infectious Diseases Research in Africa
  • Wits Reproductive Health and HIV Institute (Wits RHI)
  • Zambart

  1. About Aeras. Aeras Global TB Vaccine Foundation. Retrieved December 7, 2006, from https://web.archive.org/web/20061207055538/http://www.aeras.org/about/index.html ↩︎

  2. Research Projects. (2017, August). Infectious Diseases Institute. https://web.archive.org/web/20230517200932/https://idi.mak.ac.ug/wp-content/uploads/2017/08/Research-Projects.pdf ↩︎

  3. Other product development partnerships (PDPs). Medicines for Malaria Venture. Retrieved July 17, 2022, from https://web.archive.org/web/20220717220929/https://www.mmv.org/other-product-development-partnerships-pdps ↩︎

  4. Funders and Partners. Aeras. Retrieved July 24, 2018, from http://archive.today/2018.07.24-024017/http://www.aeras.org/pages/funders ↩︎

  5. Aeras Global TB Vaccine Foundation - Rockville, USA. Bionity. Retrieved May 12, 2023, from http://archive.today/2023.05.12-171636/https://www.bionity.com/en/associations/20656/aeras-global-tb-vaccine-foundation.html ↩︎