National COVID Cohort Collaborative
The National COVID Cohort Collaborative (N3C) is an American public-private data initiative hosted by the National Center for Advancing Translational Sciences (NCATS) and the National Center for Data to Health (CD2H). Its purpose is to "aggregate, harmonize, and make accessible vast amounts of data from health care providers nationwide to accelerate advances in COVID-19 research and clinical care."[1]
History
N3C was launched in April 2020.[2] On November 9, 2020, Datavant announced it was partnering with the Regenstrief Institute and the Indiana Clinical and Translational Sciences Institute (CTSI) to support N3C.[3]
Participants
N3C is led by the National Center for Advancing Translational Sciences (NCATS) and the National Center for Data to Health (CD2H).
Funding
In addition to core NCATS funding, N3C has been funded by:[4]
- Advanced Research Projects Agency for Health (ARPA-H)
- Biomedical Advanced Research and Development Authority (BARDA)
- National Cancer Institute (NCI)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- National Institute of General Medical Sciences (NIGMS)
- Office of the Assistant Secretary for Planning and Evaluation (ASPE)
- Office of the Director of the National Institutes of Health (OD)
- Researching COVID to Enhance Recovery (RECOVER)
Partners
Corporate, government and research partners include of N3C include:[1:1][5][6]
- Accrual to Clinical Trials Network (ACT)
- Adeptia
- Advocate Health Care
- Albert Einstein College of Medicine
- Amazon Web Services (AWS)
- Analysis Group
- ARIScience
- Ascension St. John Hospital
- Atrium Health Wake Forest Baptist Medical Center
- Auburn University
- Bar-Ilan University
- Baylor College of Medicine
- BeiGene
- Biocogniv
- Biomedical Advanced Research and Development Authority (BARDA)
- Boston Strategic Partners
- Boston University
- Bowling Green State University (BGSU)
- Brown University
- Carnegie Mellon University
- Charleston Area Medical Center (CAMC)
- Christiana Care Health System
- Cincinnati Children's Hospital Medical Center
- Colorado State University
- Columbia University
- Computer Technology Associates (CTA)
- Conovita Technologies
- Dalhousie University
- Data-Automata
- Datavant[7]
- Duke University
- East Carolina University
- Emory University
- Erasmus University Medical Center (EMC)
- Erasmus University Rotterdam (EUR)
- Florida State University
- Food and Drug Administration (FDA)
- George Mason University
- George Washington University
- Georgia Institute of Technology
- GlaxoSmithKline
- Graticule
- Harding Research
- Hartwick College
- Harvard University
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Houston Methodist Research Institute
- IBM
- Icahn School of Medicine at Mount Sinai
- Indiana University
- Institute for Systems Biology (ISB)
- IQVIA
- Jackson Laboratory
- Johns Hopkins University
- Keelung Chang Gung Memorial Hospital
- Lawrence Berkeley National Laboratory
- Lifetime Omics
- Loma Linda University (LLU)
- Louisiana Clinical and Translational Science Center (LA CaTS)
- Louisiana State University Health Sciences Center New Orleans
- Mathematica
- Mattapally Technologies
- Mayo Clinic
- MDClone
- Medical College of Wisconsin
- Medical University of South Carolina (MUSC)
- Microsoft
- Mitre Corporation
- Mount Holyoke College
- Mount Sinai Genomics
- National Cancer Institute (NCI)
- National Center for Health Statistics (NCHS)
- National Human Genome Research Institute (NHGRI)
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Patient-Centered Clinical Research Network (PCORnet)
- Nemours Children's Health
- New York University Langone Medical Center
- North Dakota State University
- Northeastern University
- Northwestern University
- Nova Southeastern University (NSU)
- Novo Nordisk
- Observational Health Data Sciences and Informatics (OHDSI)
- Office of the Assistant Secretary for Planning and Evaluation (ASPE)
- Ohio State University
- Oregon Health & Science University
- Oregon State University
- Palantir Technologies[2:1]
- Pennington Biomedical Research Center (PBRC)
- Pennsylvania State University
- Purdue University
- Regenstrief Institute[7:1]
- Research-Aid Networks
- Rocky Vista University (RVU)
- Rosalind Franklin University of Medicine and Science
- Rush University Medical Center
- Rutgers University
- Ruvos
- Sage Bionetworks
- Saskatchewan Health Authority
- Shionogi
- Southern Illinois University School of Medicine
- Stanford University
- Stony Brook University
- Sun Yat-sen University
- Syntegra
- Texas A&M University
- Texas State University
- Thomas Jefferson University
- TriNetX
- TrippBio
- United States Department of Veterans Affairs (VA)
- United States National Library of Medicine (NLM)
- University of Alabama at Birmingham
- University of Arizona
- University of Arkansas for Medical Sciences (UAMS)
- University of Basel
- University of California, Berkeley
- University of California, Davis
- University of California, Irvine
- University of California, Los Angeles (UCLA)
- University of California, Riverside
- University of California, San Diego
- University of California, San Francisco (UCSF)
- University of Canterbury
- University of Chicago
- University of Colorado Anschutz Medical Campus
- University of Delaware
- University of Florida
- University of Georgia
- University of Hawai'i System
- University of Houston
- University of Illinois Chicago (UIC)
- University of Illinois Urbana-Champaign
- University of Iowa
- University of Kansas Medical Center (KUMC)
- University of Kentucky
- University of Maryland, Baltimore County (UMBC)
- University of Massachusetts Chan Medical School
- University of Massachusetts Lowell
- University of Michigan
- University of Minnesota
- University of Mississippi Medical Center
- University of Missouri
- University of Nebraska Medical Center (UNMC)
- University of Nevada, Las Vegas
- University of New Mexico
- University of North Carolina at Chapel Hill
- University of North Dakota
- University of Oklahoma Health Sciences Center
- University of Oxford
- University of Pennsylvania
- University of Pittsburgh
- University of Puerto Rico
- University of Rochester
- University of Scranton
- University of South Carolina
- University of South Florida
- University of Southern California (USC)
- University of Sydney
- University of Tennessee Health Sciences Center (UTHCS)
- University of Texas at Arlington
- University of Texas at Austin
- University of Texas Medical Branch at Galveston
- University of Utah
- University of Vermont
- University of Virginia
- University of Washington
- Vanderbilt University Medical Center (VUMC)
- Vir Biotechnology
- Virginia Commonwealth University (VCU)
- Virginia Polytechnic Institute and State University
- Vitalant Research Institute (VRI)
- Wake Forest University Health Sciences
- Washington University in St. Louis
- Wayne State University
- Weill Cornell Graduate School of Medical Sciences
- West Virginia School of Osteopathic Medicine
- West Virginia University
- Yale University
Team
| Name | Position | Notes |
|---|---|---|
| Christopher Chute | Leadership[8] | Johns Hopkins University |
| Ken Gersing | Leadership | National Center for Advancing Translational Sciences (NCATS) |
| Melissa Haendel | Leadership | Oregon Health & Science University (OHSU), University of Colorado Anschutz Medical Campus |
| Leonie Misquitta | Leadership[9] | National Center for Advancing Translational Sciences (NCATS) |
| Tell Bennett | Collaborative Analytics | University of Colorado Anschutz Medical Campus |
| Atul Butte | Synthetic Clinical Data | University of California, San Francisco (UCSF) |
| Yooree Chae | Project Manager | Sage Bionetworks |
| Connor Cook | Program Manager | Oregon Health & Science University |
| Will Cooper | UX Designer | University of Iowa |
| Mariam Deacy | Project Manager | National Center for Advancing Translational Sciences (NCATS) |
| James Eddy | Workstream Lead | Sage Bionetworks |
| Dave Eichmann | Collaborative Analytics | University of Iowa |
| Tricia Francis | Project Manager | Johns Hopkins University |
| Rafael Fuentes | Project Manager | National Center for Advancing Translational Sciences (NCATS) |
| Alexis Graves | UI/UX Designer | University of Iowa |
| Justin Guinney | Collaborative Analytics | Sage Bionetworks |
| Erin Hernandez | Research Network Program Manager | OCHIN |
| Warren Kibbe | Collaborative Analytics | Duke University |
| Hongfang Liu | Collaborative Analytics | Mayo Clinic |
| Julie McMurry | Operational Data Program Manager | Oregon State University |
| Monica Munoz-Torres | Program Manager | Oregon State University |
| Andrew Neumann | Project Manager | Oregon State University |
| Sharon Patrick | Program Coordinator | West Virginia University (WVU) |
| Philip Payne | Synthetic Clinical Data | Washington University in St. Louis |
| Emily Pfaff | Phenotype & Data Acquisition | University of North Carolina at Chapel Hill |
| Jon Puro | Workstream Lead | OCHIN |
| Peter Robinson | Collaborative Analytics | Jackson Laboratory |
| Joel Saltz | Collaborative Analytics | Stony Brook University |
| Todd Shamaly | Project Manager | Northwestern University |
| Usman Sheikh | Project Manager | National Center for Advancing Translational Sciences (NCATS) |
| Heidi Spratt | Collaborative Analytics | University of Texas Medical Branch (UTMB) |
| Erin Stanczyk | Project Manager | Northwestern University |
| Christine Suver | Data Partnership & Governance | Sage Bionetworks |
| Peter Szolovits | Collaborative Analytics | Massachusetts Institute of Technology (MIT) |
| Nicole Venteris | Project Manager | Washington University in St. Louis |
| Andréa Volz | Communication & Engagement Manager | Oregon Health & Science University |
| Anita Walden | Assistant Director | Oregon Health & Science University |
| John Wilbanks | Data Partnership & Governance | Sage Bionetworks |
| Andrew Williams | Collaborative Analytics | Tufts University |
| Chunlei Wu | Collaborative Analytics | Scripps Research |
| Hua Xu | Collaborative Analytics | University of Texas Health Science Center at Houston |
| Liz Zampino | Program Manager | University of Washington |
External links
National COVID Cohort Collaborative (N3C). Tufts Clinical and Translational Science Institute. Retrieved June 1, 2024, from https://web.archive.org/web/20240601232238/https://www.tuftsctsi.org/research-services/informatics/national-covid-cohort-collaborative-n3c/ ↩︎ ↩︎
Gordon, L. (2021, October 4). Palantir News | NIH N3C COVID-19 Research Collaboration. Palantir. http://archive.today/2024.04.14-091041/https://www.palantir.com/newsroom/press-releases/nih-continues-collaboration-with-palantir-technologies/ ↩︎ ↩︎
Regenstrief, Indiana CTSI, Datavant Partner on NIH National COVID-19 Data Effort. (2020, November 9). Datavant. http://archive.today/2024.06.02-000049/https://www.datavant.com/press-release/regenstrief-indiana-ctsi-datavant-partner-on-nih-national-covid-19-data-effort ↩︎
Funded activities under the NCATS Clinical and Translational Science Awards (CTSA) Program with NCATS’ Appropriation and Additional CTSA Funding from Other Sources. (2024, April). National Center for Advancing Translational Sciences. https://web.archive.org/web/20240601233251/https://ncats.nih.gov/sites/default/files/2024-04/CTSA-Program-Funded-Activities-and-Other-Sources-Final-FY23_508.pdf ↩︎
Haendel, M. A., Chute, C. G., Bennett, T. D., Eichmann, D. A., Guinney, J., Kibbe, W. A., Payne, P. R. O., Pfaff, E. R., Robinson, P. N., Saltz, J. H., Spratt, H., Suver, C., Wilbanks, J., Wilcox, A. B., Williams, A. E., Wu, C., Blacketer, C., Bradford, R. L., Cimino, J. J., & Clark, M. (2020). The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment. Journal of the American Medical Informatics Association, 28(3), 427–443. https://doi.org/10.1093/jamia/ocaa196 ↩︎
N3C - Projects. National COVID Cohort Collaborative. Retrieved June 2, 2024, from https://web.archive.org/web/20240602001129/https://covid.cd2h.org/projects/ ↩︎
The National COVID Cohort Collaborative (N3C) Privacy-Preserving Record Linkage Powered by Datavant and Regenstrief Wins 2022 FedHealthIT Innovation Award. (2022, May 24). Datavant. https://web.archive.org/web/20240602000649/https://www.datavant.com/press-release/the-national-covid-cohort-collaborative-n3c-privacy-preserving-record-linkage-powered-by-datavant-and-regenstrief-wins-2022-fedhealthit-innovation-award ↩︎ ↩︎
Who We Are. National COVID Cohort Collaborative. Retrieved June 29, 2020, from http://archive.today/2020.06.29-193653/https://covid.cd2h.org/team ↩︎
Leadership & Staff. National COVID Cohort Collaborative. Retrieved October 26, 2021, from http://archive.today/2021.10.26-013537/https://covid.cd2h.org/team ↩︎