Intradigm
Intradigm Corporation was an American biotechnology company based in Rockville, Maryland.
History
Intradigm was founded in mid-2000 by Jill Glasspool-Malone, Jim Mixson and Martin Woodle.[1] The company's non-viral gene delivery technology was originally developed by Genetic Therapies, Inc. (GTI) and licensed to Intradigm by Novartis after their several attempts at gene therapy failed.[2] The license agreement was transferred to Intradigm contingent on funding from Emerging Technology Partners and Novartis’ own venture fund.
Glasspool-Malone began working on the startup in August 1999 as Managing Director, helping to secure $2.3 million in venture capital funding, setting up laboratory and office facilities, and developing the company's scientific and business development plan.[3] Intradigm entered the State of Maryland's Challenge Investment Fund program on September 20, 2000.
Intradigm closed its Series A round of funding in June 2001, receiving a $300,000 investment from the Maryland Venture Fund (MVF).[1:1] The company “entered in to a multi-year, multi-product development program” with DirectGene in December 2001 to “jointly develop products aimed at prostate and pancreatic cancer.”[4]
On November 22, 2002, Intradigm announced it had hired former Novavax CEO John Spears as its Chairman and CEO.[5][6]
On December 16, 2009, Intradigm was acquired by Silence Therapeutics.[7]
Organization
Investors in Intradigm include:[1:2][8]
- Alta Partners
- Astellas Venture Management
- Eli Lilly
- Emerging Technology Parters
- Frazier Healthcare Partners
- Maryland Venture Fund
- MediBIC Group
- MP Healthcare Venture Management
- Novartis Venture Fund
- Roche Venture Fund
Personnel
| Name | Position | Notes |
|---|---|---|
| Jill Glasspool-Malone | Co-founder and Managing Director | Wife and business partner of Robert Malone |
| Martin Woodle | Co-founder, CEO and President, Chief Scientific Advisor, Board Member | - |
| Jim Mixson | Co-founder | - |
| John Spears | CEO | Former CEO of Novavax |
| David Strickler | VP, Operations and Finance | - |
| Patrick Lu | Executive VP, Genomics | - |
| Puthupparampil Scaria | VP, Synthetic Vectors | - |
| Casimir Eitner | Chief Business Officer | - |
| Robert Riley | Director | - |
| Paul Tolstoshev | Advisory Board Member[9] | Formerly Vice President of Research at Genetic Therapies, Inc. |
| Anton Wellstein | Advisory Board Member | Georgetown University |
| Richard Heller | Advisory Board Member | University of South Florida |
| Richard Gilbert | Advisory Board Member | University of South Florida |
| Gert Storm | Advisory Board Member | Utrecht University |
| Bruce Trapnell | Advisory Board Member | University of Cincinnati, formerly VP for Virology of Genetic Therapies, Inc. |
| Dexi Liu | Advisory Board Member | University of Pittsburgh |
| Joel Cohen | Advisory Board Member | University of the Pacific |
| Joel Jessee | Advisory Board Member | Vice President of Atto Bioscience |
| Hamid Ghandehari | Advisory Board Member | University of Maryland at Baltimore |
| Archibald James Mixson | Member | University of Maryland at Baltimore |
External links
Bodnar, T. (2002). Venture Capital Funds Annual Report July 2002 (p. 27). Maryland Department of Business & Economic Development. https://web.archive.org/web/20230304190817/https://msa.maryland.gov/megafile/msa/speccol/sc5300/sc5339/000113/000000/000115/unrestricted/20030190e.pdf ↩︎ ↩︎ ↩︎
Kirchweger, G. (2003). Genetic Therapies Inc.: tight-lipped for now. Molecular Therapy, 7(3), 293. https://doi.org/10.1016/s1525-0016(03)00051-0 ↩︎
Jill Glasspool Malone. ResearchGate. Retrieved March 4, 2023, from http://archive.today/2023.03.04-082205/https://www.researchgate.net/profile/Jill-Glasspool-Malone ↩︎
Collaborations. DirectGene. Retrieved August 26, 2002, from http://archive.today/2023.03.04-200737/https://web.archive.org/web/20020826163539/http://www.directgene.com/collaborations.html ↩︎
Ex-chief of Novavax hired as Intradigm CEO. (2002, November 28). The Baltimore Sun, C2. https://www.newspapers.com/image/248431447/?terms=Intradigm&match=1 ↩︎
Intradigm appoints John A. Spears Chairman and CEO. (2002, December 2). PharmaBiz.
http://archive.today/2023.03.04-202058/http://test.pharmabiz.com/news/intradigm-appoints-john-a-spears-chairman-and-ceo-12922 ↩︎Intradigm Corporation - Crunchbase Company Profile & Funding. Crunchbase. Retrieved March 5, 2023, from https://www.crunchbase.com/organization/intradigm-corporation ↩︎
Intradigm Corporation - Funding, Financials, Valuation & Investors. Crunchbase. Retrieved March 5, 2023, from https://crunchbase.com/organization/intradigm-corporation/company_financials ↩︎
About Us. Interdigm Corporation. Retrieved May 10, 2002, from http://archive.today/2023.03.04-232009/https://web.archive.org/web/20020510051617/http://en1.endiva.net/intradigm/pub/LIT_6.asp?catid=1695 ↩︎